DataSet Record GDS4883: Expression Profiles Data Analysis Tools Sample Subsets
Title: Liver response to a metformin supplemented high fat diet deficient in methionine and choline
Cluster AnalysisGDS4883 Cluster Image
Summary: Analysis of livers of animals fed a methionine- and choline- deficient, high fat diet (MCD+HF) containing metformin. MCD+HF models non-alcoholic steatohepatitis (NASH). Results provide insight into the feasibility of using metformin, an anti-diabetic drug, to treat NASH without underlying diabetes.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
  • Kita Y, Takamura T, Misu H, Ota T et al. Metformin prevents and reverses inflammation in a non-diabetic mouse model of nonalcoholic steatohepatitis. PLoS One 2012;7(9):e43056. PMID: 23028442
Reference Series: GSE35961 Sample count: 12
Value type: count Series published: 2012/02/21