DataSet Record GDS4897: Expression Profiles Data Analysis Tools Sample Subsets
Title: Skeletal muscle of patients with inherited insulin resistance
Cluster AnalysisGDS4897 Cluster Image
Summary: Analysis of muscle from patients with a mutation (Arg1174Gln) in the tyrosine kinase domain of the insulin receptor gene (INSR). This mutation is associated with inherited insulin resistance. Results provide insight into molecular mechanisms underlying insulin resistance in skeletal muscle.
Organism: Homo sapiens
Platform: GPL571: [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
  • Kristensen JM, Skov V, Petersson SJ, Ørtenblad N et al. A PGC-1α- and muscle fibre type-related decrease in markers of mitochondrial oxidative metabolism in skeletal muscle of humans with inherited insulin resistance. Diabetologia 2014 May;57(5):1006-15. PMID: 24510228
Reference Series: GSE36297 Sample count: 16
Value type: count Series published: 2014/02/17