Stearoyl-CoA desaturase-1 deficiency effect on the skin
Summary:
Analysis of skins of animals with skin-specific deletion of Scd1. Animals with skin-specific deletion of Scd1 develop severe sebaceous gland hypoplasia that results in progressive scarring alopecia. Results provide insight into the molecular basis of Scd1-deficient skin pathology
Flowers MT, Paton CM, O'Byrne SM, Schiesser K et al. Metabolic changes in skin caused by Scd1 deficiency: a focus on retinol metabolism. PLoS One 2011 May 9;6(5):e19734. PMID: 21573029
