DataSet Record GDS4928: Expression Profiles Data Analysis Tools Sample Subsets
Title: Acetaminophen effect on thioredoxin reductase 1-null liver
Cluster AnalysisGDS4928 Cluster Image
Summary: Analysis of liver from hepatocyte-specific, thioredoxin reductase 1 (TrxR1)-null mutants treated with the pro-toxin acetaminophen. The Trx system impacts bioenergetics and drug metabolism. Results provide insight into the role of the Trx system in detoxifying certain xenobiotic challenges.
Organism: Mus musculus
Platform: GPL8321: [Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array
  • Iverson SV, Eriksson S, Xu J, Prigge JR et al. A Txnrd1-dependent metabolic switch alters hepatic lipogenesis, glycogen storage, and detoxification. Free Radic Biol Med 2013 Oct;63:369-80. PMID: 23743293
Reference Series: GSE37874 Sample count: 12
Value type: transformed count Series published: 2013/06/08