DataSet Record GDS4960: Expression Profiles Data Analysis Tools Sample Subsets
Title: ISCU myopathy
Cluster AnalysisGDS4960 Cluster Image
Summary: Analyis of vastus lateralis muscles of patients with iron-sulfur cluster scaffold homolog (ISCU) myopathy. ISCU is a rare autosomal recessive Fe-S cluster deficiency syndrome characterized by life-long exercise intolerance. Results provide insight into the molecular pathophysiology of ISCU myopathy.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
  • Crooks DR, Natarajan TG, Jeong SY, Chen C et al. Elevated FGF21 secretion, PGC-1α and ketogenic enzyme expression are hallmarks of iron-sulfur cluster depletion in human skeletal muscle. Hum Mol Genet 2014 Jan 1;23(1):24-39. PMID: 23943793
Reference Series: GSE48574 Sample count: 8
Value type: transformed count Series published: 2013/09/23