Transcription factor ETS fusion EWS/FLI1 knockdown in Ewing sarcoma cell line: time course
Summary:
Analysis of A673 Ewing Sarcoma cell line for up to 96hrs after inducible EWSR1/FLI1 knockdown. Oncogenic ETS fusions are driver mutations in diverse cancers, including Ewing sarcoma. Results provide insight into the molecular mechanisms underlying ETS-driven tumorigenesis.
GPL571:
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Citation:
Bilke S, Schwentner R, Yang F, Kauer M et al. Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer. Genome Res 2013 Nov;23(11):1797-809. PMID: 23940108
