Analysis of telomere-elongated PC-3 prostate cancer cells in the presence of exogenous human telomerase reverse transcriptase (hTERT). Forced elongation of telomeres promotes PC-3 cell differentiation. Results provide insight into the influence of telomere length on tumor malignancy.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Hirashima K, Migita T, Sato S, Muramatsu Y et al. Telomere length influences cancer cell differentiation in vivo. Mol Cell Biol 2013 Aug;33(15):2988-95. PMID: 23716593
