DataSet Record GDS4984: Expression Profiles Data Analysis Tools Sample Subsets
Title: IGHV mutated/unmutated Mantle Cell Lymphoma patients: B cell lymphocytes
Cluster AnalysisGDS4984 Cluster Image
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Summary: Analysis of B cell lymphocytes from Mantle Cell Lymphoma (MCL) patients with unmutated or mutated immunoglobulin heavy chain variable (IGHV) genes. Results provide insight into the effect of IGHV mutational status on MCL clinical features.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citations:
  • Navarro A, Clot G, Royo C, Jares P et al. Molecular subsets of mantle cell lymphoma defined by the IGHV mutational status and SOX11 expression have distinct biologic and clinical features. Cancer Res 2012 Oct 15;72(20):5307-16. PMID: 22915760
  • Palomero J, Vegliante MC, Rodríguez ML, Eguileor A et al. SOX11 promotes tumor angiogenesis through transcriptional regulation of PDGFA in mantle cell lymphoma. Blood 2014 Oct 2;124(14):2235-47. PMID: 25092176
  • Silkenstedt E, Arenas F, Colom-Sanmartí B, Xargay-Torrent S et al. Notch1 signaling in NOTCH1-mutated mantle cell lymphoma depends on Delta-Like ligand 4 and is a potential target for specific antibody therapy. J Exp Clin Cancer Res 2019 Nov 1;38(1):446. PMID: 31676012
Reference Series: GSE36000 Sample count: 38
Value type: transformed count Series published: 2013/06/25