DataSet Record GDS5014: Expression Profiles Data Analysis Tools Sample Subsets
Title: Dioxin exposure in utero effect on the hypothalamus at maturity
Cluster AnalysisGDS5014 Cluster Image
Summary: Analysis of hypothalami from postnatal day 70 male rats exposed in utero to dioxin at gestational day 15. Rats exposed to dioxin in utero exhibit a reduced pituitary synthesis of luteinizing hormone at the late fetal and early postnatal period, leading to defects in sexual behavior at adulthood.
Organism: Rattus norvegicus
Platform: GPL6101: Illumina ratRef-12 v1.0 expression beadchip
  • Takeda T, Fujii M, Hattori Y, Yamamoto M et al. Maternal exposure to dioxin imprints sexual immaturity of the pups through fixing the status of the reduced expression of hypothalamic gonadotropin-releasing hormone. Mol Pharmacol 2014 Jan;85(1):74-82. PMID: 24132183
Reference Series: GSE48100 Sample count: 6
Value type: count Series published: 2013/08/21