DataSet Record GDS5027: Expression Profiles Data Analysis Tools Sample Subsets
Title: NeOAdjuvant Herceptin (NOAH) trial: formalin-fixed, paraffin-embedded breast cancer biopsies
Cluster AnalysisGDS5027 Cluster Image
Summary: Analysis of FFPE core biopsies from pre-treated patients with HER2+ breast cancer (BC) randomized to receive neoadjuvant chemotherapy only or chemotherapy+trastuzumab (herceptin). Results provide insight into the molecular basis of survival outcomes following trastuzumab-based chemotherapy.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
  • Prat A, Bianchini G, Thomas M, Belousov A et al. Research-based PAM50 subtype predictor identifies higher responses and improved survival outcomes in HER2-positive breast cancer in the NOAH study. Clin Cancer Res 2014 Jan 15;20(2):511-21. PMID: 24443618
Reference Series: GSE50948 Sample count: 156
Value type: transformed count Series published: 2014/01/21