DataSet Record GDS5059: Expression Profiles Data Analysis Tools Sample Subsets
Title: Acute myeloid leukemia fusion oncogenes in vitro effect on primary CD34+ cells: time course
Cluster AnalysisGDS5059 Cluster Image
Summary: Analysis of CD34+ cells nucleofected (6h) or transduced (3d, 8d) with AML leukemia fusion oncogenes: AML1-ETO, MLL-AF9, PML-RARA or NUP98-HOXA9. Results provide insight into molecular mechanisms of fusion oncogene-driven leukemogenesis and early temporal patterns of gene deregulation in AML.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
  • Abdul-Nabi AM, Yassin ER, Varghese N, Deshmukh H et al. In vitro transformation of primary human CD34+ cells by AML fusion oncogenes: early gene expression profiling reveals possible drug target in AML. PLoS One 2010 Aug 27;5(8):e12464. PMID: 20805992
Reference Series: GSE57194 Sample count: 30
Value type: transformed count Series published: 2014/05/01