isp-1 and nuo-6 mutants and paraquat-treated wildtype young adults
Summary:
Analysis of wildtype worms treated with the pro-oxidant paraquat and electron transport chain mutants isp-1 and nuo-6. Results provide insight into common molecular mechanisms underlying the increased longevity in all three conditions.
GPL200:
[Celegans] Affymetrix C. elegans Genome Array
Citation:
Yee C, Yang W, Hekimi S. The intrinsic apoptosis pathway mediates the pro-longevity response to mitochondrial ROS in C. elegans. Cell 2014 May 8;157(4):897-909. PMID: 24813612