Type 1 interferon effect on primary neurons and fibroblasts from E14.5 embryos
Summary:
Analysis of primary mixed cortical/hippocampal neurons and primary fibroblasts, derived from the same E14.5 embryos and treated with interferon (IFN)-β. Results provide insight into molecular mechanisms underlying the IFN-stimulated response in the primary neuron cell population.
Kreit M, Paul S, Knoops L, De Cock A et al. Inefficient type I interferon-mediated antiviral protection of primary mouse neurons is associated with the lack of apolipoprotein l9 expression. J Virol 2014 Apr;88(7):3874-84. PMID: 24453359
