U2OS osteosarcoma cell line response to strigolactone analogs ST362 and MEB55: 6 hours
Summary:
Analysis of U2OS cells treated with strigolactone (SL) analog ST362 or MEB55 for 6hr. SL is a plant hormone. SL analogs potently inhibit growth of breast cancer cells. Results provide insight into molecular mechanisms underlying the anti-tumorigenic effects of SL analogs towards cancer cells.
Pollock CB, McDonough S, Wang VS, Lee H et al. Strigolactone analogues induce apoptosis through activation of p38 and the stress response pathway in cancer cell lines and in conditionally reprogrammed primary prostate cancer cells. Oncotarget 2014 Mar 30;5(6):1683-98. PMID: 24742967
