Analysis of whole blood samples from patients with ankylosing spondylitis (AS). AS is a chronic inflammatory rheumatic disease characterized by inflammation that leads to bone resorption and bone formation. Results provide insight into the molecular pathogenesis of AS.
Pimentel-Santos FM, Ligeiro D, Matos M, Mourão AF et al. Whole blood transcriptional profiling in ankylosing spondylitis identifies novel candidate genes that might contribute to the inflammatory and tissue-destructive disease aspects. Arthritis Res Ther 2011 Apr 7;13(2):R57. PMID: 21470430