Striatal-enriched protein tyrosine phosphatase (STEP) knockout effect on striatum
Summary:
Analysis of striatum from striatal-enriched protein tyrosine phosphatase (STEP)+/- and -/- littermates. Brain-specific tyrosine phosphatase STEP is associated with de-phosphorylation of several key neuronal signaling proteins. Results provide insight into role of STEP in synaptic plasticity.
Reinhart VL, Nguyen T, Gerwien R Jr, Kuhn M et al. Downstream effects of striatal-enriched protein tyrosine phosphatase reduction on RNA expression in vivo and in vitro. Neuroscience 2014 Oct 10;278:62-9. PMID: 25130559
