Neurospheres derived from adult and embryonic brain regions
Summary:
Analysis of neurospheres derived from adult brain regions (neocortex, striatum, and subventricular zone) and dorsal and ventral forebrain neural tubes and spinal cord from E14.5 embryos. Results provide insight into molecular mechanisms underlying neurogenesis of the mammalian brain.
Grande A, Sumiyoshi K, López-Juárez A, Howard J et al. Environmental impact on direct neuronal reprogramming in vivo in the adult brain. Nat Commun 2013;4:2373. PMID: 23974433