DataSet Record GDS5271: Expression Profiles Data Analysis Tools Sample Subsets
Title: Lipopolysaccharide effect on transmembrane protease, serine 6 deficient liver
Cluster AnalysisGDS5271 Cluster Image
Summary: Analysis of liver from Tmprss6 knockouts (KO) and iron-deficient WT littermates treated with LPS to induce acute inflammation. Tmprss6 KOs are iron-deficient with high levels of hepcidin, a key iron regulator. Results provide insight into molecular basis of the Tmprss6 KO inflammatory response.
Organism: Mus musculus
Platform: GPL6887: Illumina MouseWG-6 v2.0 expression beadchip
  • Riba M, Rausa M, Sorosina M, Cittaro D et al. A strong anti-inflammatory signature revealed by liver transcription profiling of Tmprss6-/- mice. PLoS One 2013;8(7):e69694. PMID: 23922777
Reference Series: GSE46287 Sample count: 12
Value type: count Series published: 2013/10/09