DataSet Record GDS5309: Expression Profiles Data Analysis Tools Sample Subsets
Title: Sotrastaurin effect on mantle cell lymphoma cell lines
Cluster AnalysisGDS5309 Cluster Image
Summary: Analysis of various mantle cell lymphoma (MCL) lines treated with sotrastaurin (STN). Jeko-1 and Mino are STN-sensitive cell lines; Z-138 and Maver-1 are STN-insensitive cell lines. STN is a pan-protein kinase C (PKC) inhibitor. Results provide insight into the molecular response to PKC inhibition.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
  • Rahal R, Frick M, Romero R, Korn JM et al. Pharmacological and genomic profiling identifies NF-κB-targeted treatment strategies for mantle cell lymphoma. Nat Med 2014 Jan;20(1):87-92. PMID: 24362935
Reference Series: GSE42549 Sample count: 16
Value type: count Series published: 2013/12/01