Beta-catenin depletion effect on pancreatic cancer cell line
Summary:
Analysis of AsPc1 pancreatic adenocarcinoma cells depleted for beta-catenin. Dysregulation of Wnt/β-catenin signaling is implicated in the pathogenesis of cancers. Results compared to those from AsPC1 cells treated with the CREB-binding protein inhibitor ICG-001 (GDS5323).
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Arensman MD, Telesca D, Lay AR, Kershaw KM et al. The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. Mol Cancer Ther 2014 Oct;13(10):2303-14. PMID: 25082960
