p38-alpha deficient keratinocyte response to ultraviolet-B in vitro
Summary:
Analysis of p38-alpha deficient keratinocytes exposed to ultraviolet-B (UVB) for 4 hours in vitro. p38-alpha is a mitogen-activated protein kinase. Inflammation underlies UVB's various detrimental effects. Results provide insight into the role of p38-alpha in UVB-induced inflammation.
Sano Y, Park JM. Loss of epidermal p38α signaling prevents UVR-induced inflammation via acute and chronic mechanisms. J Invest Dermatol 2014 Aug;134(8):2231-2240. PMID: 24662766