DataSet Record GDS5350: Expression Profiles Data Analysis Tools Sample Subsets
Title: RB1-depleted osteoblast response to ionizing radiation: time course
Cluster AnalysisGDS5350 Cluster Image
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Summary: Analysis of RB1-depleted primary osteoblasts exposed to 4 Gy of ionizing radiation (IR) for up to 24 hours. IR exposure and germline mutations in RB1 are risk factors for developing osteosarcoma. Results provide insight into the role of RB1 in the response of osteoblasts to IR.
Organism: Homo sapiens
Platform: GPL6244: [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
  • Kansara M, Leong HS, Lin DM, Popkiss S et al. Immune response to RB1-regulated senescence limits radiation-induced osteosarcoma formation. J Clin Invest 2013 Dec;123(12):5351-60. PMID: 24231354
Reference Series: GSE50532 Sample count: 36
Value type: transformed count Series published: 2013/09/14