NF-kappaB subunit p65/RelA deficiency effect on hematopoietic stem cells
Summary:
Analysis of lineage-negative, c-kit+ Sca-1+ Flk2- (LSKF) hematopoietic stem cells (HSCs) lacking the NF-kappaB subunit p65/RelA. LSKF HSCs purified from the bone marrow. Results provide insight into the role of NF-kappaB subunit p65/RelA in HSCs.
Stein SJ, Baldwin AS. Deletion of the NF-κB subunit p65/RelA in the hematopoietic compartment leads to defects in hematopoietic stem cell function. Blood 2013 Jun 20;121(25):5015-24. PMID: 23670180
