DataSet Record GDS5385: Expression Profiles Data Analysis Tools Sample Subsets
Title: Lipopolysaccharide effect on tumor progression locus 2 kinase-deficient macrophages
Cluster AnalysisGDS5385 Cluster Image
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Summary: Analysis of tumor progression locus 2 (Tpl2)-deficient bone marrow derived macrophages (BMDMs) stimulated with lipopolysaccharide (LPS) for 4 hrs. Tpl2 (Map3k8) is a serine/threonine kinase critical in innate immunity. Results provide insight into the role of Tpl2 in BMDMs during acute inflammation.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Rowley SM, Kuriakose T, Dockery LM, Tran-Nguyen T et al. Tumor progression locus 2 (Tpl2) kinase promotes chemokine receptor expression and macrophage migration during acute inflammation. J Biol Chem 2014 May 30;289(22):15788-97. PMID: 24713702
Reference Series: GSE48338 Sample count: 8
Value type: transformed count Series published: 2014/06/03