DataSet Record GDS5406: Expression Profiles Data Analysis Tools Sample Subsets
Title: Imatinib mesylate effect on EOL-1 eosinophilic leukemia cell line
Cluster AnalysisGDS5406 Cluster Image
Summary: Analysis of EOL-1 cells treated with imatinib mesylate (1uM, 6h). EOL-1 cells carry the platelet derived growth factor receptor α (PDGFRA)/FIP1L1 fusion and exhibit constitutive PDGFRA activation. Results provide insight into the molecular effects of inhibiting PDGFRA signaling by imatinib.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
  • Piccaluga PP, Rossi M, Agostinelli C, Ricci F et al. Platelet-derived growth factor alpha mediates the proliferation of peripheral T-cell lymphoma cells via an autocrine regulatory pathway. Leukemia 2014 Aug;28(8):1687-97. PMID: 24480986
Reference Series: GSE53633 Sample count: 4
Value type: transformed count Series published: 2013/12/25