Analysis of peripheral blood-purified CD19-positive B cells activated with CD40. CD40 is a potent activation stimulus for the induction of B cell-mediated antigen presentation and cytokine production. Results provide insight into molecular mechanisms underlying B cell activation via CD40.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Shimabukuro-Vornhagen A, Zoghi S, Liebig TM, Wennhold K et al. Inhibition of protein geranylgeranylation specifically interferes with CD40-dependent B cell activation, resulting in a reduced capacity to induce T cell immunity. J Immunol 2014 Nov 15;193(10):5294-305. PMID: 25311809
