DataSet Record GDS5421: Expression Profiles Data Analysis Tools Sample Subsets
Title: Transcription factor E2-2 haplodeficiency effect on systemic lupus erythematosus model: splenocytes
Cluster AnalysisGDS5421 Cluster Image
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Summary: Analysis of splenocytes from WT, B6.Sle1.Sle3 (lupus mice) and B6.Sle1.Sle3 Tcf4+/− (Sle/het) mice haplodeficient for the transcription factor E2-2 (Tcf4). E2-2 is a specific regulator of plasmacytoid dendritic cell (pDC) development. Results provide insight into role of pDC in SLE pathogenesis.
Organism: Mus musculus
Platform: GPL6246: [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]
Citation:
  • Sisirak V, Ganguly D, Lewis KL, Couillault C et al. Genetic evidence for the role of plasmacytoid dendritic cells in systemic lupus erythematosus. J Exp Med 2014 Sep 22;211(10):1969-76. PMID: 25180061
Reference Series: GSE57324 Sample count: 8
Value type: count Series published: 2014/07/30