Circadian modulators SHARP1/SHARP2 deficiency effect on cortex: time course
Summary:
Analysis of cortex from SHARP1/2 double null mutants at ZT4 (wake phase) and ZT16 (sleep phase). bHLH transcription factors SHARP1 (DEC2, BHLHE41) and SHARP2 (DEC1, BHLHE40) are circadian modulators. Results provide insight into the molecular contributions of SHARP1/SHARP2 to the sleep-wake cycle.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Baier PC, Brzózka MM, Shahmoradi A, Reinecke L et al. Mice lacking the circadian modulators SHARP1 and SHARP2 display altered sleep and mixed state endophenotypes of psychiatric disorders. PLoS One 2014;9(10):e110310. PMID: 25340473
