Analysis of liver from C57Bl/6J males fed isocaloric diets containing sucrose or palatinose. Sucrose is a high glycemic index (GI) sugar; palatinose is a low GI sugar. Results provide insight into molecular mechanisms underlying the role of sucrose in the development of non-alcoholic fatty liver.
Keyhani-Nejad F, Irmler M, Isken F, Wirth EK et al. Nutritional strategy to prevent fatty liver and insulin resistance independent of obesity by reducing glucose-dependent insulinotropic polypeptide responses in mice. Diabetologia 2015 Feb;58(2):374-83. PMID: 25348610
