MLL2-depleted epidermal keratinocyte response to the induction of differentiation in vitro
Summary:
Analysis of MLL2-depleted neonatal epidermal keratinocytes following treatment with 1.8 mM calcium for 24 hours to induce differentiation. Histone H3K4 methyltransferase MLL2 is a trithorax group protein. Results provide insight into the role of MLL2 in keratinocyte differentiation.
GPL6244:
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Citation:
Hopkin AS, Gordon W, Klein RH, Espitia F et al. GRHL3/GET1 and trithorax group members collaborate to activate the epidermal progenitor differentiation program. PLoS Genet 2012;8(7):e1002829. PMID: 22829784
