DataSet Record GDS5455: Expression Profiles Data Analysis Tools Sample Subsets
Title: Ribosomal S6 kinase 2 deficiency effect on TNF-α transgenic model of inflammatory arthritis: fibroblast-like synoviocytes
Cluster AnalysisGDS5455 Cluster Image
Summary: Analysis of primary fibroblast-like synoviocytes from human tumor necrosis factor-α transgenics (hTNFtg) knocked out for ribosomal S6 kinase (Rsk2). Rsk2 belongs to the p90(RSK) family of serine/threonine kinases. Results provide insight into the role of Rsk2 in TNF-induced synovial hyperplasia.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
  • Derer A, Böhm C, Grötsch B, Grün JR et al. Rsk2 controls synovial fibroblast hyperplasia and the course of arthritis. Ann Rheum Dis 2016 Feb;75(2):413-21. PMID: 25414238
  • Menssen A, Edinger G, Grün JR, Haase U et al. SiPaGene: A new repository for instant online retrieval, sharing and meta-analyses of GeneChip expression data. BMC Genomics 2009 Mar 5;10:98. PMID: 19265543
Reference Series: GSE52992 Sample count: 6
Value type: count Series published: 2014/12/04