Interleukin-33 effect on dual-specificity phosphatase 5-deficient bone marrow derived eosinophils
Summary:
Analysis of BM-derived eosinophils isolated from dual-specificity phosphatase 5-deficient mice and stimulated with IL-33. DUSP5 is a growth factor‐inducible phosphatase preferentially expressed in immune cells. Results provide insight into the role of DUSP5 in IL-33 signaling in eosinophils.
Holmes DA, Yeh JH, Yan D, Xu M et al. Dusp5 negatively regulates IL-33-mediated eosinophil survival and function. EMBO J 2015 Jan 13;34(2):218-35. PMID: 25398911
