DataSet Record GDS5502: Expression Profiles Data Analysis Tools Sample Subsets
Title: Small molecule GW8510 effect on pancreatic alpha cell
Cluster AnalysisGDS5502 Cluster Image
Summary: Analysis of pancreatic alpha cells treated with GW8510, a CDK2 inhibitor. Insulin expression is largely restricted to pancreatic beta cells. These results, together with those of GDS5503, provide insight into potential mechanisms of insulin induction by non-beta pancreatic cell types.
Organism: Mus musculus
Platform: GPL8321: [Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array
  • Fomina-Yadlin D, Kubicek S, Vetere A, He KH et al. GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activity. PLoS One 2012;7(1):e28808. PMID: 22242153
Reference Series: GSE31102 Sample count: 6
Value type: count Series published: 2011/08/02