5-azacytidine effect on mesenchymal progenitor cell line
Summary:
Analysis of C2C12 mesenchymal progenitor cells treated with 5-azacytidine (5AC). 5AC is a DNA methylation inhibitor and induces genomic demethylation. Results provide insight into the role of DNA demethylation on skeletal myotube maturation.
Hupkes M, Jonsson MK, Scheenen WJ, van Rotterdam W et al. Epigenetics: DNA demethylation promotes skeletal myotube maturation. FASEB J 2011 Nov;25(11):3861-72. PMID: 21795504