Sirtuin-1 activator resveratrol effect on adult secondary neurospheres
Summary:
Analysis of adult secondary neurospheres derived from hippocampal neural stem cells/neural progenitor cells and treated with resveratrol, an activator of NAD-dependent histone deacetylase Sirtuin-1 (Sirt1). Results provide insight into the role of Sirt1 in adult hippocampal neurogenesis.
Ma CY, Yao MJ, Zhai QW, Jiao JW et al. SIRT1 suppresses self-renewal of adult hippocampal neural stem cells. Development 2014 Dec;141(24):4697-709. PMID: 25468938
