DataSet Record GDS5613: Expression Profiles Data Analysis Tools Sample Subsets
Title: All-trans retinoic acid effect on U937 myeloid cells overexpressing ecotropic virus integration site 1
Cluster AnalysisGDS5613 Cluster Image
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Summary: Analysis of EVI1-overexpressing U937 myeloid cells treated with ATRA. EVI1 overexpression is associated with poor prognosis in myeloid leukemias; ATRA is a myeloid differentiation inducing agent. Results provide insight into the potential interplay between EVI1 and ATRA in myeloid cells.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citations:
  • Steinmetz B, Hackl H, Slabáková E, Schwarzinger I et al. The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid. Cell Cycle 2014;13(18):2931-43. PMID: 25486480
  • [No authors listed] Corrigendum. Cell Cycle 2015;14(11):1759. PMID: 26036413
Reference Series: GSE66854 Sample count: 12
Value type: transformed count Series published: 2015/03/13