DataSet Record GDS5621: Expression Profiles Data Analysis Tools Sample Subsets
Title: Estradiol effect on MCF7 breast cancer cells expressing progesterone receptor-B
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Summary: Analysis of estradiol-treated, progesterone receptor (PR)-low/estrogen receptor (ER)+ MCF7 breast cancer cells stably-expressing PR-B. Progesterone and estrogen are major drivers of breast cancer. Results provide insight into the molecular cross-talk between ER and PR-B in breast cancer.
Organism: Homo sapiens
Platform: GPL10558: Illumina HumanHT-12 V4.0 expression beadchip
Citation:
  • Daniel AR, Gaviglio AL, Knutson TP, Ostrander JH et al. Progesterone receptor-B enhances estrogen responsiveness of breast cancer cells via scaffolding PELP1- and estrogen receptor-containing transcription complexes. Oncogene 2015 Jan 22;34(4):506-15. PMID: 24469035
Reference Series: GSE45643 Sample count: 12
Value type: transformed count Series published: 2015/03/15