DataSet Record GDS5624: Expression Profiles Data Analysis Tools Sample Subsets
Title: Epigenetic modifying reagents effect on a progressive hearing loss model: whole cochlea
Cluster AnalysisGDS5624 Cluster Image
Summary: Analysis of cochlea from 4 wk old DBA/2J males (a model of progressive hearing loss) injected for 8 wks with a combination of epigenetic modifiers l-methionine and valproic acid. Results provide insight into the effect of epigenetic modifications on the molecular mechanisms underlying hearing loss.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
  • Mutai H, Miya F, Fujii M, Tsunoda T et al. Attenuation of progressive hearing loss in DBA/2J mice by reagents that affect epigenetic modifications is associated with up-regulation of the zinc importer Zip4. PLoS One 2015;10(4):e0124301. PMID: 25875282
  • Miya F, Mutai H, Fujii M, Boroevich KA et al. Gene expression profiling of DBA/2J mice cochleae treated with l-methionine and valproic acid. Genom Data 2015 Sep;5:323-5. PMID: 26484279
Reference Series: GSE62173 Sample count: 16
Value type: transformed count Series published: 2015/04/15