DataSet Record GDS5625: Expression Profiles Data Analysis Tools Sample Subsets
Title: DNA methyltransferase inhibitor 5-aza-2’-deoxycytidine effect on oral cancer cell lines
Cluster AnalysisGDS5625 Cluster Image
Summary: Analysis of oral squamous cell carcinoma (OSCC) cell lines: OC3, SAS, SCC-15, and HSC3, treated with 5-aza-2’-deoxycytidine (AzC), an inhibitor of DNA methyltransferase. Results provide insight into potential tumor suppressor genes silenced by DNA hypermethylation in OSCC.
Organism: Homo sapiens
Platform: GPL6883: Illumina HumanRef-8 v3.0 expression beadchip
  • Lee CH, Wong TS, Chan JY, Lu SC et al. Epigenetic regulation of the X-linked tumour suppressors BEX1 and LDOC1 in oral squamous cell carcinoma. J Pathol 2013 Jul;230(3):298-309. PMID: 23362108
  • Chou ST, Peng HY, Mo KC, Hsu YM et al. MicroRNA-486-3p functions as a tumor suppressor in oral cancer by targeting DDR1. J Exp Clin Cancer Res 2019 Jun 28;38(1):281. PMID: 31253192
Reference Series: GSE38823 Sample count: 16
Value type: count Series published: 2015/04/01