DataSet Record GDS5626: Expression Profiles Data Analysis Tools Sample Subsets
Title: pH1N1 influenza virus infection of interferon regulatory factor 7-deficient peripheral blood mononuclear cells: time course
Cluster AnalysisGDS5626 Cluster Image
Summary: Analysis of PBMCs isolated from an IRF7-deficient patient and infected with influenza A/CA/4/2009 for up to 16 hrs. Transcription factor IRF7 amplifies type I and III interferon response to viruses. Results provide insight into the role of IRF7 in antiviral immunity.
Organism: Homo sapiens
Platform: GPL10558: Illumina HumanHT-12 V4.0 expression beadchip
  • Ciancanelli MJ, Huang SX, Luthra P, Garner H et al. Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency. Science 2015 Apr 24;348(6233):448-53. PMID: 25814066
Reference Series: GSE66486 Sample count: 18
Value type: transformed count Series published: 2015/04/07