Phorbol myristate acetate plus ionomycin activation effect on primary T lymphoblasts and their exosomes
Summary:
Analysis of primary T lymphoblasts and derived exosomes after activation with PMA plus ionomycin. Exosomes contain specific RNA species and can be functionally transferred to recipient cells. Results provide insight into molecular mechanisms underlying the selective sorting of RNA into exosomes.
GPL6480:
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version)
Citation:
Villarroya-Beltri C, Gutiérrez-Vázquez C, Sánchez-Cabo F, Pérez-Hernández D et al. Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs. Nat Commun 2013;4:2980. PMID: 24356509
