DataSet Record GDS5651: Expression Profiles Data Analysis Tools Sample Subsets
Title: DNA methyltransferase inhibitor 5-Aza-2’deoxycytidine effect on partially-ligated left carotid artery
Cluster AnalysisGDS5651 Cluster Image
Summary: Analysis of arteries from C57BL/6 males pretreated with DNMT inhibitor 5Aza for 2 wk, then subjected to partial carotid ligation (PCL) and continued 5Aza treatment for 1 wk after ligation. PCL induces disturbed blood flow. Results provide insight into molecular basis of atherosclerosis development.
Organism: Mus musculus
Platform: GPL6887: Illumina MouseWG-6 v2.0 expression beadchip
  • Dunn J, Qiu H, Kim S, Jjingo D et al. Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis. J Clin Invest 2014 Jul;124(7):3187-99. PMID: 24865430
Reference Series: GSE56143 Sample count: 12
Value type: count Series published: 2014/03/25