DataSet Record GDS5662: Expression Profiles Data Analysis Tools Sample Subsets
Title: Histone demethylase KDM3A-deficiency effect on estrogen-stimulated breast cancer cells in vitro
Cluster AnalysisGDS5662 Cluster Image
Summary: Analysis of estrogen receptor (ER)-positive breast cancer cell line MCF-7 depleted for KDM3A (histone lysine demethylase 3A) then treated with estrogen. Histone lysine methylation is an important regulator of transcription. Results provide insight into role of KDM3A in ER signaling in breast cancer.
Organism: Homo sapiens
Platform: GPL10558: Illumina HumanHT-12 V4.0 expression beadchip
  • Wade MA, Jones D, Wilson L, Stockley J et al. The histone demethylase enzyme KDM3A is a key estrogen receptor regulator in breast cancer. Nucleic Acids Res 2015 Jan;43(1):196-207. PMID: 25488809
Reference Series: GSE68918 Sample count: 11
Value type: transformed count Series published: 2015/05/16