Notch1 stimulation effect on glioblastoma stem cell cultures
Summary:
Analysis of Gb4 and Gb7 glioma cancer stem cells following forced expression of the Notch1 intracellular domain (NICD) to activate the Notch1 signaling pathway. Results provide insight into a role for the Notch1 pathway in glioblastoma stem cell plasticity and angiogenic properties.
GPL11532:
[HuGene-1_1-st] Affymetrix Human Gene 1.1 ST Array [transcript (gene) version]
Citation:
Guichet PO, Guelfi S, Teigell M, Hoppe L et al. Notch1 stimulation induces a vascularization switch with pericyte-like cell differentiation of glioblastoma stem cells. Stem Cells 2015 Jan;33(1):21-34. PMID: 24898819
