DataSet Record GDS5677: Expression Profiles Data Analysis Tools Sample Subsets
Title: Mutant isocitrate dehydrogenase 1 effect on hepatoblasts grown on uncoated plates
Cluster AnalysisGDS5677 Cluster Image
Summary: Analysis of mutant IDH1 (R132C)-expressing hepatoblasts that were grown on uncoated plates to induce hepatocyte differentiation. IDH genes are frequently mutated in intrahepatic cholangiocarcinoma (IHCC). Results provide insight into the role of IDH1 in hepatocyte differentiation.
Organism: Mus musculus
Platform: GPL8321: [Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array
  • Saha SK, Parachoniak CA, Ghanta KS, Fitamant J et al. Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer. Nature 2014 Sep 4;513(7516):110-4. PMID: 25043045
Reference Series: GSE57002 Sample count: 4
Value type: count Series published: 2014/04/30