Interstitial fluid flow effect on noninvasive and invasive ERBB2-positive breast cancer cells
Summary:
Analysis of non-invasive NeuN cells and invasive NeuT cells (i.e., MCF10A cells overexpressing wild-type ERBB2 or a constitutively active mutant of ERBB2, respectively) treated with IFF. Results provide insight into the molecular pathways activated by IFF in ERBB2-positive breast cancer cells.
Tchafa AM, Ta M, Reginato MJ, Shieh AC. EMT Transition Alters Interstitial Fluid Flow-Induced Signaling in ERBB2-Positive Breast Cancer Cells. Mol Cancer Res 2015 Apr;13(4):755-64. PMID: 25566992
