DataSet Record GDS5804: Expression Profiles Data Analysis Tools Sample Subsets
Title: PI3K/mTOR Inhibitor NVP-BEZ235 and taxotere effects on prostate cancer xenograft tumors
Cluster AnalysisGDS5804 Cluster Image
Summary: Analysis of DU145 xenograft tumors in NOD/SCID mice treated with NVP-BEZ235, taxotere, or both. NVP-BEZ235 targets prostate cancer progenitor cells. Taxotere targets the bulk tumor. Results provide insight into potential biomarkers associated with cancer stem cells in these xenograft tumors.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
  • Cojoc M, Peitzsch C, Kurth I, Trautmann F et al. Aldehyde Dehydrogenase Is Regulated by β-Catenin/TCF and Promotes Radioresistance in Prostate Cancer Progenitor Cells. Cancer Res 2015 Apr 1;75(7):1482-94. PMID: 25670168
Reference Series: GSE49232 Sample count: 4
Value type: count Series published: 2015/01/23