Retinoic acid teratogenic effect on cranial neural crest: time course
Summary:
Expression profiling of cranial neural crest exposed to 1 uM retinoic acid (RA) at various lengths of time up to 48 hours. Neural crest obtained from 8.5 days postcoitum ICR embryos. Results provide insight into developmental pathways affected upon exposure to teratogenic concentrations of RA.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Williams SS, Mear JP, Liang HC, Potter SS et al. Large-scale reprogramming of cranial neural crest gene expression by retinoic acid exposure. Physiol Genomics 2004 Oct 4;19(2):184-97. PMID: 15466718