DataSet Record GDS841: Expression Profiles Data Analysis Tools Sample Subsets
Title: Adult acute myeloid leukemia: bone marrow and peripheral blood expression profiles (SHCO)
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Summary: Part of a study profiling 54 bone marrow and 65 peripheral blood samples from 116 adults with acute myeloid leukemia (AML). Results identify distinct gene expression signatures that correlate with clinical outcomes. Signatures used to construct a clinical outcome predictor using 133 genes.
Organism: Homo sapiens
Platform: GPL317: SHCO
Citations:
  • Bullinger L, Döhner K, Bair E, Fröhling S et al. Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia. N Engl J Med 2004 Apr 15;350(16):1605-16. PMID: 15084693
  • Greiner J, Schmitt M, Li L, Giannopoulos K et al. Expression of tumor-associated antigens in acute myeloid leukemia: Implications for specific immunotherapeutic approaches. Blood 2006 Dec 15;108(13):4109-17. PMID: 16931630
  • Bullinger L, Ehrich M, Döhner K, Schlenk RF et al. Quantitative DNA methylation predicts survival in adult acute myeloid leukemia. Blood 2010 Jan 21;115(3):636-42. PMID: 19903898
Reference Series: GSE425 Sample count: 26
Value type: log ratio Series published: 2004/04/15