DataSet Record GDS972: Expression Profiles Data Analysis Tools Sample Subsets
Title: Methylprednisolone effect on liver: time course (RAE230A)
Cluster AnalysisGDS972 Cluster Image
Summary: Expression profiling of liver from animals treated with methylprednisolone. Liver examined at various time points up to 168 hours following methylprednisolone treatment. Results provide insight into prednisone pharmacodynamics.
Organism: Rattus norvegicus
Platform: GPL341: [RAE230A] Affymetrix Rat Expression 230A Array
  • Jin JY, Almon RR, DuBois DC, Jusko WJ. Modeling of corticosteroid pharmacogenomics in rat liver using gene microarrays. J Pharmacol Exp Ther 2003 Oct;307(1):93-109. PMID: 12808002
  • Hazra A, DuBois DC, Almon RR, Snyder GH et al. Pharmacodynamic modeling of acute and chronic effects of methylprednisolone on hepatic urea cycle genes in rats. Gene Regul Syst Bio 2008 Feb 14;2:1-19. PMID: 19787073
Reference Series: GSE487 Sample count: 44
Value type: count Series published: 2003/07/16